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(Until 13:30 on Saturdays, closed on Sundays and public holidays)
Provided by HDC Atlas Clinic
Physician in charge: Yoshihiko Suzuki, diabetes specialist
Chapter 3: Why do you lose 20%? The surprising mechanism
How Zepp Bound works
The reason ZepBound has such revolutionary weight loss benefits is because it utilizes the body's natural systems.
Natural appetite control
It acts on the brain's satiety center, creating a state where you "naturally don't want to eat" rather than "holding back from eating." It also slows down stomach activity, which helps you feel fuller for longer and reduces the desire to snack.
The synergistic effect of the two hormones
By simultaneously enhancing the effects of two hormones, GLP-1 (appetite suppression and blood sugar stabilization) and GIP (improvement of insulin sensitivity), it produces significant effects that cannot be achieved by either hormone alone.
Interestingly, although GIP is thought to promote fat accumulation, in ZepBound, its interaction with GLP-1 actually contributes to weight loss, a phenomenon known as the "GIP paradox."
Effectiveness for Japanese people
It is particularly effective for Japanese people, who tend to accumulate visceral fat, and clinical trials have shown a 35-40% reduction in visceral fat area.
Important Note: The Need for Continuity
The SURMOUNT-4 trial found that over 80% of patients experienced rebound effects when they stopped taking the medication . Because the medication controls appetite through hormonal effects rather than altering the body's constitution, continued use is necessary.